Avanafil, sold under the brand name Stendra, is a medication used to treat erectile dysfunction (ED) in men. It belongs to the drug class of impotence agents and works by improving blood flow to the penis, which helps in achieving and maintaining an erection.

Mechanism of Action

Avanafil works by inhibiting phosphodiesterase type 5 (PDE5), an enzyme that is responsible for breaking down cGMP, a substance that relaxes smooth muscles and increases blood flow to the penis. By inhibiting PDE5, avanafil helps increase the levels of cGMP, which promotes the relaxation of smooth muscles and blood flow to the penis, resulting in an erection.

STENDRA (avanafil) is a particular inhibitor of cGMP-explicit PDE5.

 Avanafil is assigned artificially as (S)- 4- [(3-Chloro-4-methoxybenzyl) amino] -2- [2-(hydroxymethyl)- 1-pyrrolidinyl]-N (2-pyrimidinylmethyl)- 5-pyrimidinecarboxamide

Avanafil happens as white translucent powder, atomic equation C23H26ClN7O3 and sub-atomic load of 483.95 and is marginally dissolvable in ethanol, for all intents and purposes insoluble in water, solvent in 0.1 mol/L hydrochloric corrosive. STENDRA, for oral organization, is provided as oval, light-yellow tablets containing 50 mg, 100 mg, or 200 mg avanafil debossed with measurement qualities.

Notwithstanding the dynamic fixing, avanafil, every tablet contains the accompanying latent fixings: mannitol, fumaric corrosive, hydroxypropyl cellulose, low subbed hydroxypropyl cellulose, calcium carbonate, magnesium stearate, and ferric oxide yellow.

1. Stendra: This is the brand name of avanafil medication that is widely available in the market. It is known for its fast-acting and long-lasting effects in treating erectile dysfunction.
2. Avana: Another popular brand name of avanafil medication is Avana. It is used to improve the sexual performance of men by increasing the blood flow to the penis.
3. Top Avana: This medication is a combination of avanafil and dapoxetine, which helps to treat both erectile dysfunction and premature ejaculation. It is a popular choice among men who suffer from both of these conditions.
4. Avagra: This is another brand name of avanafil that is widely used in the treatment of erectile dysfunction. It is known for its effectiveness in improving sexual performance.
5. Avanafil: This is the generic name of the medication, and it is also available in the market under various other brand names. It is a highly effective treatment option for erectile dysfunction.